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Prof Yaohe Wang


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Be Part of Research - Trial Details - Personalised cancer vaccines
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Personalised cancer vaccines

Not Recruiting

Open to: All Genders

Age: Adult

Middlesex London

Medical Conditions

Pancreatic cancer

This information is provided directly by researchers and we recognise that it isn't always easy to understand. We are working with researchers to improve the accessibility of this information.


Pancreatic cancer causes the uncontrolled growth of cells in a large gland of the digestive system. Pancreatic cancer has a very poor prognosis (forcast) with an overall survival rate of less than 5%. Current treatments are ineffective and even if the patient responds to initial treatments, relapse (the cancer coming back) is common due to the survival of small populations of resistant cancer cells. The immune system is capable of recognising and eliminating invading organisms by virtue of differences in their appearance when compared to normal components of the body. Cancer cells also have a different appearance compared to normal cells. However, these differences are often too small and weak to stimulate the immune system sufficiently to respond effectively to eliminate the tumour. The aim of this study is to analyse the small differences between healthy and cancer cells in pancreatic cancer patients by analysing genetic information from pancreatic cancer cells and see their ability to stimulate an immune response.

Start dates may differ between countries and research sites. The research team are responsible for keeping the information up-to-date.  

The recruitment start and end dates are as follows:

01 Aug 2016 20 Jul 2018

Publications

2022 Results article in https://pubmed.ncbi.nlm.nih.gov/35655709/ (added 28/09/2022)

Blood samples are taken from participants and are analysed for genetic information with respect to their ability to stimulate an immune response against cancer.


Adults aged 17 to 66 who fulfill the NHS blood donation requirements.

You can take part if:



You may not be able to take part if:


Same as NHS BT criteria, which are:1. receiving treatment2. taking medication3. travelling outside of the UK4. tattoos5. pregnancy6. illness7. cancer8. received blood, blood products or organs


Below are the locations for where you can take part in the trial. Please note that not all sites may be open.

  • NHS Blood and Transplant. Blood Donation Centre Edgware
    Edgware Community Hospital Burnt Oak Broadway Edgware
    Middlesex
    HA8 0AD
  • NHS Blood and Transplant. Tooting Blood Donor Centre
    75 Cranmer Street Tooting
    London
    SW17 0RB

Not provided at time of registration.

Prof Yaohe Wang



The study is sponsored by Joint Research Management Office, Queen Mary University of London and funded by Pancreatic Cancer Research Fund.



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Read full details for Trial ID: ISRCTN58774519
Last updated 28 September 2022

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